The All Progressives Congress (APC) got fewer votes in the region during the 2019 presidential election and the minister described this as voting against the party.
In an interview with The Sun, Amaechi said the Igbo has nothing to bring in negotiating for 2023 presidency.
The minister said the region is completely out of national politics and if Igbo are not found in national politics, it will be to the detriment of their children.
Ahead of the 2019 elections, Boss Mustapha, secretary to the government of the federation (SGF), has also said the chances of Igbo clinching the presidential seat would depend on the vote the region turns in for President Muhammadu Buhari in 2019.
Since the return of democracy in 1999, Nigeria is yet to have a president of Igbo extraction